BIRLAMCHI IMMUN TANQISLIGI BO‘LGAN BOLALARDA IMMUN DISFUNKSIYA VA SEPSIS OG‘IRLIGI O‘RTASIDAGI BOG‘LIQLIK: RETROSPEKTIV TAHLIL
Annotatsiya
Sepsis, ayniqsa birlamchi immun tanqisligi bo‘lgan bolalar orasida, pediatrik bemorlarda kasallanish va o‘limning asosiy sabablaridan biri bo‘lib qolmoqda. Bunday bemorlar tug‘ma immun nuqsonlari sababli og‘ir infeksiyalarga yuqori moyillik, atipik klinik ko‘rinishlar va kasallikning tez og‘irlashish xavfi bilan tavsiflanadi. Mazkur tadqiqot Toshkent shahar bolalar klinikasida davolangan holatlarning retrospektiv tahlili asosida PID bo‘lgan bolalarda sepsisning klinik va immunologik xususiyatlarini o‘rganishga qaratilgan. Tahlilda klinik va laborator ma’lumotlar, immunologik ko‘rsatkichlar, qo‘zg‘atuvchilar, davolash usullari va natijalar baholandi. Humoral va hujayraviy immunitetdagi nuqsonlar hamda ularning sepsis og‘irligi bilan bog‘liqligi alohida ko‘rib chiqildi. Natijalar PID bo‘lgan bolalarda sepsis ko‘pincha og‘ir kechishini, tashxis kech qo‘yilishini va shifoxonada qolish muddati uzayishini ko‘rsatdi.
Kalit so'zlar
sepsis, birlamchi immun tanqisligi, bolalar, klinik xususiyatlar, immunologik buzilishlar, retrospektiv tahlil
Adabiyotlar ro'yxati
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